8JUL

Cryo-EM structure of SIDT1 in complex with phosphatidic acid

Summary for 8JUL

Entry DOI	10.2210/pdb8jul/pdb
EMDB information	36661
Descriptor	SID1 transmembrane family member 1, ZINC ION, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, ... (4 entities in total)
Functional Keywords	sid-1 transmembrane family member 1, crest family, phospholipase d, rna uptake, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	189048.68
Authors	Sun, C.R.,Xu, D.,Li, Q.,Zhou, C.Z.,Chen, Y. (deposition date: 2023-06-26, release date: 2023-11-15, Last modification date: 2024-01-24)
Primary citation	Sun, C.R.,Xu, D.,Yang, F.,Hou, Z.,Luo, Y.,Zhang, C.Y.,Shan, G.,Huang, G.,Yao, X.,Chen, Y.,Li, Q.,Zhou, C.Z. Human SIDT1 mediates dsRNA uptake via its phospholipase activity. Cell Res., 34:84-87, 2024 Cited by PubMed: 37932444 DOI: 10.1038/s41422-023-00889-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.92 Å)

Structure validation