8JUL

Cryo-EM structure of SIDT1 in complex with phosphatidic acid

8JUL の概要

• エントリーDOI: 10.2210/pdb8jul/pdb
• EMDBエントリー: 36661
• 分子名称: SID1 transmembrane family member 1, ZINC ION, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: sid-1 transmembrane family member 1, crest family, phospholipase d, rna uptake, membrane protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 189048.68

構造登録者

Sun, C.R.,Xu, D.,Li, Q.,Zhou, C.Z.,Chen, Y. (登録日: 2023-06-26, 公開日: 2023-11-15, 最終更新日: 2024-10-23)

• 主引用文献: Sun, C.R.,Xu, D.,Yang, F.,Hou, Z.,Luo, Y.,Zhang, C.Y.,Shan, G.,Huang, G.,Yao, X.,Chen, Y.,Li, Q.,Zhou, C.Z.; Human SIDT1 mediates dsRNA uptake via its phospholipase activity.; Cell Res., 34:84-87, 2024; PubMed: 37932444; DOI: 10.1038/s41422-023-00889-x

実験手法

ELECTRON MICROSCOPY (2.92 Å)