8JTM
CNE55.664 trimer in complex with broadly neutralizing HIV antibody PGT145
Summary for 8JTM
Entry DOI | 10.2210/pdb8jtm/pdb |
EMDB information | 36649 |
Descriptor | gp120 protein of HIV envelope trimer, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | hiv, envelope trimer, broadly neutralizing antibody, pgt145, cryo-em, viral protein |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 8 |
Total formula weight | 292018.97 |
Authors | Chatterjee, A.,Chen, C.,Lee, K.,Mangala Prasad, V. (deposition date: 2023-06-22, release date: 2023-10-25, Last modification date: 2024-05-08) |
Primary citation | Hodge, E.A.,Chatterjee, A.,Chen, C.,Naika, G.S.,Laohajaratsang, M.,Mangala Prasad, V.,Lee, K.K. An HIV-1 broadly neutralizing antibody overcomes structural and dynamic variation through highly focused epitope targeting. Npj Viruses, 1:2-2, 2023 Cited by PubMed: 38665238DOI: 10.1038/s44298-023-00002-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (5.14 Å) |
Structure validation
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