8JTM

CNE55.664 trimer in complex with broadly neutralizing HIV antibody PGT145

8JTM の概要

• エントリーDOI: 10.2210/pdb8jtm/pdb
• EMDBエントリー: 36649
• 分子名称: gp120 protein of HIV envelope trimer, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: hiv, envelope trimer, broadly neutralizing antibody, pgt145, cryo-em, viral protein
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 292018.97

構造登録者

Chatterjee, A.,Chen, C.,Lee, K.,Mangala Prasad, V. (登録日: 2023-06-22, 公開日: 2023-10-25, 最終更新日: 2024-05-08)

• 主引用文献: Hodge, E.A.,Chatterjee, A.,Chen, C.,Naika, G.S.,Laohajaratsang, M.,Mangala Prasad, V.,Lee, K.K.; An HIV-1 broadly neutralizing antibody overcomes structural and dynamic variation through highly focused epitope targeting.; Npj Viruses, 1:2-2, 2023; PubMed: 38665238; DOI: 10.1038/s44298-023-00002-4

実験手法

ELECTRON MICROSCOPY (5.14 Å)