8JP2
Crystal structure of AKR1C1 in complex with DFV
Summary for 8JP2
Entry DOI | 10.2210/pdb8jp2/pdb |
Descriptor | Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 7-HYDROXY-2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE, ... (4 entities in total) |
Functional Keywords | aldo-keto reductase 1c1;20alpha-hydroxysteroid dehydrogenase; complex;inhibitor;flavanone, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 37838.99 |
Authors | |
Primary citation | Liu, H.,Yao, Z.,Sun, M.,Zhang, C.,Huang, Y.Y.,Luo, H.B.,Wu, D.,Zheng, X. Inhibition of AKR1Cs by liquiritigenin and the structural basis. Chem.Biol.Interact., 385:110654-110654, 2023 Cited by PubMed: 37666442DOI: 10.1016/j.cbi.2023.110654 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report