8JNQ

Crystal structure of cytochrome P450 CftA from Streptomyces torulosus NRRL B-3889, in complex with a substrate compound c

8JNQ の概要

• エントリーDOI: 10.2210/pdb8jnq/pdb
• 分子名称: Cytochrome P450, (1Z,3E,5E,7S,8R,10S,11R,13R,15R,16E,18E,25S)-11-ethyl-2,7-dihydroxy-10-methyl-21,26-diazatetracyclo[23.2.1.09,13.08,15]octacosa-1(2),3,5,16,18-pentaene-20,27,28-trione, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
• 機能のキーワード: actinomadura viridis, hydrolase, lobophorin, deglycosylation, oxidoreductase
• 由来する生物種: Streptomyces torulosus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45224.75

構造登録者

Jiang, P.,Zhang, L.P.,Zhang, C.S. (登録日: 2023-06-06, 公開日: 2023-11-15, 最終更新日: 2023-12-20)

• 主引用文献: Jiang, P.,Jin, H.,Zhang, G.,Zhang, W.,Liu, W.,Zhu, Y.,Zhang, C.,Zhang, L.; A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates.; Angew.Chem.Int.Ed.Engl., 62:e202310728-e202310728, 2023; PubMed: 37917570; DOI: 10.1002/anie.202310728

実験手法

X-RAY DIFFRACTION (2 Å)