8JJ8

Cryo-EM structure of the beta2AR-mBRIL/1b3 Fab/Glue complex with a partial agonist

Summary for 8JJ8

Entry DOI	10.2210/pdb8jj8/pdb
EMDB information	36342
Descriptor	Beta-2 adrenergic receptor,Soluble cytochrome b562, ~{N}-[5-[(1~{R})-2-[[(2~{R})-1-(4-methoxyphenyl)propan-2-yl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide (2 entities in total)
Functional Keywords	complex, chimera, gpcr, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	1
Total formula weight	51938.51
Authors	He, B.B.,Zhong, Y.X.,Guo, Q.,Tao, Y.Y. (deposition date: 2023-05-29, release date: 2023-09-06, Last modification date: 2024-01-03)
Primary citation	Guo, Q.,He, B.,Zhong, Y.,Jiao, H.,Ren, Y.,Wang, Q.,Ge, Q.,Gao, Y.,Liu, X.,Du, Y.,Hu, H.,Tao, Y. A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20:74-82, 2024 Cited by PubMed: 37580554 DOI: 10.1038/s41589-023-01389-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation