8JDP

Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid

8JDP の概要

• エントリーDOI: 10.2210/pdb8jdp/pdb
• 分子名称: Probable D-lactate dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, DEAMINOHYDROXYVALINE, ... (4 entities in total)
• 機能のキーワード: d-lactate dehydrogenase, ldhd, 2-hydroxyacid, oxidoreductase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 51289.47

構造登録者

Jin, S.,Chen, X.,Yang, J.,Ding, J. (登録日: 2023-05-15, 公開日: 2023-10-18, 最終更新日: 2024-02-21)

• 主引用文献: Jin, S.,Chen, X.,Yang, J.,Ding, J.; Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.; Nat Commun, 14:6638-6638, 2023; PubMed: 37863926; DOI: 10.1038/s41467-023-42456-3

実験手法

X-RAY DIFFRACTION (1.6 Å)