8JA1

ASFV Topoisomerase ATPase domain in complex with AMP-PNP and Mg2+ (oxidized form)

Summary for 8JA1

• Entry DOI: 10.2210/pdb8ja1/pdb
• Descriptor: DNA topoisomerase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
• Functional Keywords: ghkl nucleotide-binding fold, topoisomerase, amp-pnp, asfv, isomerase
• Biological source: African swine fever virus
• Total number of polymer chains: 1
• Total formula weight: 45994.06

Authors

Chang, C.-W.,Pang, A.H.,Tsai, M.-D. (deposition date: 2023-05-05, release date: 2024-02-07, Last modification date: 2024-04-17)

• Primary citation: Chang, C.M.,Wang, S.C.,Wang, C.H.,Pang, A.H.,Yang, C.H.,Chang, Y.K.,Wu, W.J.,Tsai, M.D.; A unified view on enzyme catalysis by cryo-EM study of a DNA topoisomerase.; Commun Chem, 7:45-45, 2024; PubMed: 38418525; DOI: 10.1038/s42004-024-01129-y

Experimental method

X-RAY DIFFRACTION (1.14 Å)