8J8H

SPARTA monomer bound with guide-target, state 2

Summary for 8J8H

• Entry DOI: 10.2210/pdb8j8h/pdb
• EMDB information: 36070
• Descriptor: Piwi domain-containing protein, TIR domain-containing protein, RNA (5'-R(P*UP*GP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ... (5 entities in total)
• Functional Keywords: sparta, ago, tir, dna binding protein/dna/rna, dna binding protein-dna-rna complex
• Biological source: Thermoflavifilum thermophilum; More
• Total number of polymer chains: 4
• Total formula weight: 133018.71

Authors

Li, Z.X.,Guo, L.J.,Huang, P.P.,Xiao, Y.B.,Chen, M.R. (deposition date: 2023-05-01, release date: 2024-03-06, Last modification date: 2024-04-10)

• Primary citation: Guo, L.,Huang, P.,Li, Z.,Shin, Y.C.,Yan, P.,Lu, M.,Chen, M.,Xiao, Y.; Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.; Nat.Chem.Biol., 20:512-520, 2024; PubMed: 37932527; DOI: 10.1038/s41589-023-01478-0

Experimental method

ELECTRON MICROSCOPY (3.4 Å)