8J75
Human high-affinity choline transporter CHT1 in the HC-3-bound outward-facing open conformation, monomeric state
Summary for 8J75
Entry DOI | 10.2210/pdb8j75/pdb |
EMDB information | 36027 |
Descriptor | High affinity choline transporter 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium) (3 entities in total) |
Functional Keywords | cht1, slc5a7, high affinity choline transporter, choline transporter, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 64240.22 |
Authors | |
Primary citation | Qiu, Y.,Gao, Y.,Huang, B.,Bai, Q.,Zhao, Y. Transport mechanism of presynaptic high-affinity choline uptake by CHT1. Nat.Struct.Mol.Biol., 31:701-709, 2024 Cited by PubMed: 38589607DOI: 10.1038/s41594-024-01259-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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