8J6X
Crystal structure of SARS-CoV2 N-NTD complexed with 5-Benzyloxygramine derivative (P3-8)
Summary for 8J6X
| Entry DOI | 10.2210/pdb8j6x/pdb |
| Descriptor | Nucleoprotein, ~{N}-methyl-~{N}-[(5-phenylmethoxy-1~{H}-indol-3-yl)methyl]propan-1-amine (3 entities in total) |
| Functional Keywords | severe acute respiratory syndrome coronavirus 2 nucleocapsid protein 5-benzyloxygramine, viral protein |
| Biological source | Severe acute respiratory syndrome coronavirus 2 |
| Total number of polymer chains | 4 |
| Total formula weight | 68520.54 |
| Authors | Hong, J.Y.,Hou, M.H. (deposition date: 2023-04-26, release date: 2024-02-07, Last modification date: 2024-03-06) |
| Primary citation | Hong, J.Y.,Lin, S.C.,Kehn-Hall, K.,Zhang, K.M.,Luo, S.Y.,Wu, H.Y.,Chang, S.Y.,Hou, M.H. Targeting protein-protein interaction interfaces with antiviral N protein inhibitor in SARS-CoV-2. Biophys.J., 123:478-488, 2024 Cited by PubMed: 38234090DOI: 10.1016/j.bpj.2024.01.013 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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