8J6I

Cryo-EM structure of thehydroxycarboxylic acid receptor 2-Gi protein complex bound MK-6892

8J6I の概要

• エントリーDOI: 10.2210/pdb8j6i/pdb
• EMDBエントリー: 36005
• 分子名称: Hydroxycarboxylic acid receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
• 機能のキーワード: hydroxycarboxylic acid receptor 2, gpcr, niacin, mk-6892, gsk256073, membrane protein, membrane protein-immune system complex, membrane protein/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 146976.05

構造登録者

Yuan, Q.,Zhu, S.,Duan, J.,Xu, H.E.,Duan, X. (登録日: 2023-04-26, 公開日: 2024-04-03)

• 主引用文献: Zhu, S.,Yuan, Q.,Li, X.,He, X.,Shen, S.,Wang, D.,Li, J.,Cheng, X.,Duan, X.,Xu, H.E.,Duan, J.; Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2.; Cell Rep, 42:113406-113406, 2023; PubMed: 37952153; DOI: 10.1016/j.celrep.2023.113406

実験手法

ELECTRON MICROSCOPY (2.92 Å)