8IZG

Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with 5-HMBPP

8IZG の概要

• エントリーDOI: 10.2210/pdb8izg/pdb
• 分子名称: Butyrophilin subfamily 3 member A1, DI(HYDROXYETHYL)ETHER, [(2E)-3-(hydroxymethyl)hexa-2,5-dienyl] phosphono hydrogen phosphate, ... (5 entities in total)
• 機能のキーワード: butyrophilin, signaling protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23180.16

構造登録者

Yang, Y.Y.,Yi, S.M.,Huang, J.W.,Chen, C.C.,Guo, R.T. (登録日: 2023-04-07, 公開日: 2023-09-13, 最終更新日: 2023-10-18)

• 主引用文献: Yuan, L.,Ma, X.,Yang, Y.,Qu, Y.,Li, X.,Zhu, X.,Ma, W.,Duan, J.,Xue, J.,Yang, H.,Huang, J.W.,Yi, S.,Zhang, M.,Cai, N.,Zhang, L.,Ding, Q.,Lai, K.,Liu, C.,Zhang, L.,Liu, X.,Yao, Y.,Zhou, S.,Li, X.,Shen, P.,Chang, Q.,Malwal, S.R.,He, Y.,Li, W.,Chen, C.,Chen, C.C.,Oldfield, E.,Guo, R.T.,Zhang, Y.; Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.; Nature, 621:840-848, 2023; PubMed: 37674084; DOI: 10.1038/s41586-023-06525-3

実験手法

X-RAY DIFFRACTION (1.6 Å)