8IYK

Tail tip conformation 1 of phage lambda tail

This is a non-PDB format compatible entry.

Summary for 8IYK

• Entry DOI: 10.2210/pdb8iyk/pdb
• Related: 8IYD
• EMDB information: 35824
• Descriptor: Tail tube protein, Tail tip protein M, Tip attachment protein J, ... (7 entities in total)
• Functional Keywords: bacteriophage, caudovirales, siphoviridae, tail complex, delivery device, macromolecular assembly, phage lambda, cryo-em, viral protein
• Biological source: Escherichia phage lambda (Bacteriophage lambda); More
• Total number of polymer chains: 42
• Total formula weight: 1493765.52

Authors

Wang, J.W.,Wang, C. (deposition date: 2023-04-05, release date: 2023-10-18, Last modification date: 2024-01-24)

Primary citation

Wang, C.,Duan, J.,Gu, Z.,Ge, X.,Zeng, J.,Wang, J.
Architecture of the bacteriophage lambda tail.
Structure, 32:35-, 2024

PubMed Abstract: Bacteriophage lambda has a double-stranded DNA genome and a long, flexible, non-contractile tail encoded by a contiguous block of 11 genes downstream of the head genes. The tail allows host recognition and delivery of viral DNA from the head shell to the cytoplasm of the infected cell. Here, we present a high-resolution structure of the tail complex of bacteriophage lambda determined by cryoelectron microscopy. Most component proteins of the lambda tail were determined at the atomic scale. The structure sheds light on the molecular organization of the extensively studied tail of bacteriophage lambda.

PubMed: 37918400
DOI: 10.1016/j.str.2023.10.006

Experimental method

ELECTRON MICROSCOPY (2.95 Å)