8ITG
Crystal structure of lasso peptide epimerase MslH in complexed with precursor peptide variant MslAW21G
Summary for 8ITG
Entry DOI | 10.2210/pdb8itg/pdb |
Descriptor | Poly-gamma-glutamate synthesis protein (Capsule biosynthesis protein), Tricyclic peptide MS-271, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total) |
Functional Keywords | epimerase, mslh, msla, lasso peptide, ripps, ms-271, isomerase |
Biological source | Streptomyces griseorubiginosus More |
Total number of polymer chains | 2 |
Total formula weight | 51920.67 |
Authors | Nakashima, Y.,Hiroyuki, M. (deposition date: 2023-03-22, release date: 2023-06-21, Last modification date: 2023-08-23) |
Primary citation | Nakashima, Y.,Kawakami, A.,Ogasawara, Y.,Maeki, M.,Tokeshi, M.,Dairi, T.,Morita, H. Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism. Nat Commun, 14:4752-4752, 2023 Cited by PubMed: 37550286DOI: 10.1038/s41467-023-40232-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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