8IPL

The structure of human mitochondrial methyltransferase METTL15 with RBFA and SAM

Summary for 8IPL

Entry DOI	10.2210/pdb8ipl/pdb
Descriptor	Putative ribosome-binding factor A, mitochondrial, 12S rRNA N4-methylcytidine (m4C) methyltransferase, S-ADENOSYLMETHIONINE, ... (4 entities in total)
Functional Keywords	human mitochondrial methyltransferase mettl15, ribosomal protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	41982.37
Authors	Lv, M.Q.,Zhou, W.W. (deposition date: 2023-03-14, release date: 2024-01-03, Last modification date: 2024-02-14)
Primary citation	Lv, M.,Zhou, W.,Hao, Y.,Li, F.,Zhang, H.,Yao, X.,Shi, Y.,Zhang, L. Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15. Cell Discov, 10:11-11, 2024 Cited by PubMed: 38291322 DOI: 10.1038/s41421-023-00634-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation