8IPK

The structure of human mitochondrial methyltransferase METTL15 with SAM

8IPK の概要

• エントリーDOI: 10.2210/pdb8ipk/pdb
• 分子名称: 12S rRNA N4-methylcytidine (m4C) methyltransferase, S-ADENOSYLMETHIONINE, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: human mitochondrial methyltransferase mettl15, ribosomal protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38535.43

構造登録者

Lv, M.Q.,Zhou, W.W. (登録日: 2023-03-14, 公開日: 2024-01-03, 最終更新日: 2024-02-14)

• 主引用文献: Lv, M.,Zhou, W.,Hao, Y.,Li, F.,Zhang, H.,Yao, X.,Shi, Y.,Zhang, L.; Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15.; Cell Discov, 10:11-11, 2024; PubMed: 38291322; DOI: 10.1038/s41421-023-00634-z

実験手法

X-RAY DIFFRACTION (1.9 Å)