8INW

Crystal Structure of SARS-CoV-2 Main Protease (Mpro) K90R Mutant in Complex with Inhibitor nirmatrelvir

Summary for 8INW

• Entry DOI: 10.2210/pdb8inw/pdb
• Descriptor: 3C-like proteinase, (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide (3 entities in total)
• Functional Keywords: sars-cov-2, mutant, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• Total number of polymer chains: 1
• Total formula weight: 34355.10

Authors

Lin, M.,Liu, X. (deposition date: 2023-03-10, release date: 2024-03-13)

• Primary citation: Lin, M.,Liu, X.; Crystal Structure of SARS-CoV-2 Main Protease (Mpro) K90R Mutant in Complex with Inhibitor nirmatrelvir; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)