8IJ3
Cryo-EM structure of human HCAR2-Gi complex without ligand (apo state)
Summary for 8IJ3
Entry DOI | 10.2210/pdb8ij3/pdb |
EMDB information | 35463 |
Descriptor | Hydroxycarboxylic acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (5 entities in total) |
Functional Keywords | complex, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 143883.48 |
Authors | |
Primary citation | Pan, X.,Ye, F.,Ning, P.,Zhang, Z.,Li, X.,Zhang, B.,Wang, Q.,Chen, G.,Gao, W.,Qiu, C.,Wu, Z.,Li, J.,Zhu, L.,Xia, J.,Gong, K.,Du, Y. Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2. Cell Discov, 9:118-118, 2023 Cited by PubMed: 38012147DOI: 10.1038/s41421-023-00610-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.28 Å) |
Structure validation
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