8IF4
Structure of human alpha-2/delta-1 without mirogabalin
Summary for 8IF4
| Entry DOI | 10.2210/pdb8if4/pdb |
| EMDB information | 35400 |
| Descriptor | Voltage-dependent calcium channel subunit alpha-2/delta-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
| Functional Keywords | gabapentinoid, cache domain, cryo-em, membrane protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 125722.29 |
| Authors | Kozai, D.,Numoto, N.,Fujiyoshi, Y. (deposition date: 2023-02-17, release date: 2023-04-05, Last modification date: 2023-04-12) |
| Primary citation | Kozai, D.,Numoto, N.,Nishikawa, K.,Kamegawa, A.,Kawasaki, S.,Hiroaki, Y.,Irie, K.,Oshima, A.,Hanzawa, H.,Shimada, K.,Kitano, Y.,Fujiyoshi, Y. Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human alpha 2 delta 1, a Voltage-Gated Calcium Channel Subunit. J.Mol.Biol., 435:168049-168049, 2023 Cited by PubMed: 36933823DOI: 10.1016/j.jmb.2023.168049 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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