8ID3

Cryo-EM structure of the 9-hydroxystearic acid bound GPR120-Gi complex

8ID3 の概要

• エントリーDOI: 10.2210/pdb8id3/pdb
• EMDBエントリー: 35356
• 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: gpcr, gpr120, complex, fatty acid hormones, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 156758.64

構造登録者

Mao, C.,Xiao, P.,Tao, X.,Qin, J.,He, Q.,Zhang, C.,Yu, X.,Zhang, Y.,Sun, J. (登録日: 2023-02-12, 公開日: 2023-03-15, 最終更新日: 2023-05-03)

• 主引用文献: Mao, C.,Xiao, P.,Tao, X.N.,Qin, J.,He, Q.T.,Zhang, C.,Guo, S.C.,Du, Y.Q.,Chen, L.N.,Shen, D.D.,Yang, Z.S.,Zhang, H.Q.,Huang, S.M.,He, Y.H.,Cheng, J.,Zhong, Y.N.,Shang, P.,Chen, J.,Zhang, D.L.,Wang, Q.L.,Liu, M.X.,Li, G.Y.,Guo, Y.,Xu, H.E.,Wang, C.,Zhang, C.,Feng, S.,Yu, X.,Zhang, Y.,Sun, J.P.; Unsaturated bond recognition leads to biased signal in a fatty acid receptor.; Science, 380:eadd6220-eadd6220, 2023; PubMed: 36862765; DOI: 10.1126/science.add6220

実験手法

ELECTRON MICROSCOPY (3.1 Å)