8I7W
Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
Summary for 8I7W
Entry DOI | 10.2210/pdb8i7w/pdb |
EMDB information | 35235 |
Descriptor | Human hydroxycarboxylic acid receptor 2,Hydroxycarboxylic acid receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | gpcr, g-protein, membrane protein, signaling |
Biological source | Homo sapiens More |
Total number of polymer chains | 5 |
Total formula weight | 168636.52 |
Authors | |
Primary citation | Park, J.H.,Kawakami, K.,Ishimoto, N.,Ikuta, T.,Ohki, M.,Ekimoto, T.,Ikeguchi, M.,Lee, D.S.,Lee, Y.H.,Tame, J.R.H.,Inoue, A.,Park, S.Y. Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2. Nat Commun, 14:7150-7150, 2023 Cited by PubMed: 37932263DOI: 10.1038/s41467-023-42764-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.39 Å) |
Structure validation
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