8I69
Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 5-Fluoroorotic acid and Citric acid, Form I
8I69 の概要
エントリーDOI | 10.2210/pdb8i69/pdb |
分子名称 | Uracil-DNA glycosylase, 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CITRIC ACID, ... (5 entities in total) |
機能のキーワード | dna repair, base excision repair, inhibitor-complex, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
由来する生物種 | Mycobacterium tuberculosis H37Rv |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 26303.89 |
構造登録者 | |
主引用文献 | Kesharwani, S.,Raj, P.,Paul, A.,Roy, K.,Bhanot, A.,Mehta, A.,Gopal, A.,Varshney, U.,Gopal, B.,Sundriyal, S. Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258:115604-115604, 2023 Cited by PubMed: 37399710DOI: 10.1016/j.ejmech.2023.115604 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2 Å) |
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