8I5L

Crystal structure of P domain from norovirus GI.4 capsid protein in complex with broad specificity antibody single-chain Fv fragment CV-2F5.

Summary for 8I5L

• Entry DOI: 10.2210/pdb8i5l/pdb
• Descriptor: Capsid protein, scFv fragment (3 entities in total)
• Functional Keywords: norovirus, p-domain, capsid, viral protein, single-chain fv fragment, antibody-protein complex
• Biological source: Norovirus GI.4 Hu/NLV/Chiba 407/1987/JP; More
• Total number of polymer chains: 5
• Total formula weight: 156357.58

Authors

Kato-Murayama, M.,Murayama, K.,Shirouzu, M. (deposition date: 2023-01-26, release date: 2024-01-31, Last modification date: 2024-05-08)

• Primary citation: Kimura-Someya, T.,Katsura, K.,Kato-Murayama, M.,Hosaka, T.,Uchikubo-Kamo, T.,Ihara, K.,Hanada, K.,Sato, S.,Murayama, K.,Kataoka, M.,Shirouzu, M.,Someya, Y.; Structural analyses of the GI.4 norovirus by cryo-electron microscopy and X-ray crystallography revealing binding sites for human monoclonal antibodies.; J.Virol., :e0019724-e0019724, 2024; PubMed: 38593321; DOI: 10.1128/jvi.00197-24

Experimental method

X-RAY DIFFRACTION (2.7 Å)