8I4C

Cryo-EM structure of U46619-bound ABCC4

Summary for 8I4C

• Entry DOI: 10.2210/pdb8i4c/pdb
• EMDB information: 35169
• Descriptor: ATP-binding cassette sub-family C member 4, (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid (2 entities in total)
• Functional Keywords: apo-form, abc transport, atp-binding cassette, multidrug resistance proteins, mrp, atp-binding cassette subfamily c, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 150044.41

Authors

Chen, Y.,Wang, L.,Hou, W.T.,Zhou, C.Z.,Chen, Y.,Li, Q. (deposition date: 2023-01-19, release date: 2023-05-24, Last modification date: 2024-07-03)

• Primary citation: Chen, Y.,Wang, L.,Hou, W.T.,Zhou, C.Z.,Chen, Y.,Li, Q.; Cryo-EM structure ofABCC4; Nat Cardiovasc Res, 2023

Experimental method

ELECTRON MICROSCOPY (3.08 Å)