8I4A

Cryo-EM structure of dipyridamole-bound ABCC4

Summary for 8I4A

• Entry DOI: 10.2210/pdb8i4a/pdb
• EMDB information: 35167
• Descriptor: ATP-binding cassette sub-family C member 4, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol (2 entities in total)
• Functional Keywords: apo-form, abc transport, atp-binding cassette, multidrug resistance proteins, mrp, atp-binding cassette subfamily c, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 150198.55

Authors

Chen, Y.,Wang, L.,Hou, W.T.,Zhou, C.Z.,Chen, Y.,Li, Q. (deposition date: 2023-01-19, release date: 2023-05-24, Last modification date: 2024-07-03)

• Primary citation: Chen, Y.,Wang, L.,Hou, W.T.,Zhou, C.Z.,Chen, Y.,Li, Q.; Cryo-EM structure ofABCC4; Nat Cardiovasc Res, 2023

Experimental method

ELECTRON MICROSCOPY (3.4 Å)