8I10

Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Vasopressin V2 receptor, V2R (Local refine)

Summary for 8I10

Entry DOI	10.2210/pdb8i10/pdb
EMDB information	35115
Descriptor	Beta-arrestin-2, Fab30 Heavy Chain, Fab30 Light Chain, ... (4 entities in total)
Functional Keywords	gpcr, arrestin, signaling protein, signaling protein-immune system complex, signaling protein/immune system
Biological source	Bos taurus (cattle) More
Total number of polymer chains	12
Total formula weight	299148.09
Authors	Maharana, J.,Sarma, P.,Yadav, M.K.,Banerjee, R.,Shukla, A.K. (deposition date: 2023-01-12, release date: 2023-05-17, Last modification date: 2024-07-17)
Primary citation	Maharana, J.,Sarma, P.,Yadav, M.K.,Saha, S.,Singh, V.,Saha, S.,Chami, M.,Banerjee, R.,Shukla, A.K. Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation. Mol.Cell, 83:2091-2107.e7, 2023 Cited by PubMed: 37209686 DOI: 10.1016/j.molcel.2023.04.025 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.96 Å)

Structure validation