8I0P

The cryo-EM structure of human pre-Bact complex

This is a non-PDB format compatible entry.

Summary for 8I0P

• Entry DOI: 10.2210/pdb8i0p/pdb
• EMDB information: 35105
• Descriptor: Pre-mRNA-processing-splicing factor 8, Crooked neck-like protein 1, DNA/RNA-binding protein KIN17, ... (47 entities in total)
• Functional Keywords: spliceosome, pre-bact complex, rna splicing, prp2, activation, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 51
• Total formula weight: 2845662.38

Authors

Zhan, X.,Lu, Y.,Shi, Y. (deposition date: 2023-01-11, release date: 2024-07-31, Last modification date: 2024-08-07)

• Primary citation: Zhan, X.,Lu, Y.,Shi, Y.; Molecular basis for the activation of human spliceosome.; Nat Commun, 15:6348-6348, 2024; PubMed: 39068178; DOI: 10.1038/s41467-024-50785-0

Experimental method

ELECTRON MICROSCOPY (3.4 Å)