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8HKN

Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to approved drug Fluzoparib

Summary for 8HKN
Entry DOI10.2210/pdb8hkn/pdb
DescriptorPoly [ADP-ribose] polymerase 2, GLYCEROL, Fluzoparib, ... (4 entities in total)
Functional Keywordsdna adp-ribosyltransferase 2, parp2, fluzoparib, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight81060.80
Authors
Wang, X.Y.,Zhou, J.,Xu, B.L. (deposition date: 2022-11-27, release date: 2024-05-01)
Primary citationWang, X.Y.,Zhou, J.,Xu, B.L.
Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to approved drug Fluzoparib
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

227111

数据于2024-11-06公开中

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