8HC4

SARS-CoV-2 wildtype spike trimer (6P) in complex with 3 YB9-258 Fabs and 3 R1-32 Fabs (3 RBD up)

8HC4 の概要

• エントリーDOI: 10.2210/pdb8hc4/pdb
• EMDBエントリー: 34651
• 分子名称: Spike glycoprotein, Heavy chain of R1-32 Fab, Light chain of R1-32 Fab, ... (7 entities in total)
• 機能のキーワード: spike protein, rbd, antibody, fab, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 15
• 化学式量合計: 690657.10

構造登録者

Liu, B.,Gao, X.,Chen, Q.,Li, Z.,Su, M.,He, J.,Xiong, X. (登録日: 2022-11-01, 公開日: 2023-01-25, 最終更新日: 2023-05-03)

• 主引用文献: Yu, H.,Liu, B.,Zhang, Y.,Gao, X.,Wang, Q.,Xiang, H.,Peng, X.,Xie, C.,Wang, Y.,Hu, P.,Shi, J.,Shi, Q.,Zheng, P.,Feng, C.,Tang, G.,Liu, X.,Guo, L.,Lin, X.,Li, J.,Liu, C.,Huang, Y.,Yang, N.,Chen, Q.,Li, Z.,Su, M.,Yan, Q.,Pei, R.,Chen, X.,Liu, L.,Hu, F.,Liang, D.,Ke, B.,Ke, C.,Li, F.,He, J.,Wang, M.,Chen, L.,Xiong, X.,Tang, X.; Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants.; Nat Commun, 14:1058-1058, 2023; PubMed: 36828833; DOI: 10.1038/s41467-023-36761-0

実験手法

ELECTRON MICROSCOPY (3.54 Å)