8H4R

The Crystal Structure of CDK3 and CyclinE1 Complex with Dinaciclib from Biortus

Summary for 8H4R

Entry DOI	10.2210/pdb8h4r/pdb
Descriptor	Glutathione S-transferase class-mu 26 kDa isozyme,Cyclin-dependent kinase 3, G1/S-specific cyclin-E1, 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium, ... (7 entities in total)
Functional Keywords	complex, cell cycle
Biological source	Schistosoma japonicum (Blood fluke) More
Total number of polymer chains	2
Total formula weight	98848.06
Authors	Gui, W.,Wang, F.,Cheng, W.,Gao, J.,Huang, Y.,Ouyang, Z. (deposition date: 2022-10-11, release date: 2023-10-11, Last modification date: 2024-10-16)
Primary citation	Gui, W.,Wang, F.,Cheng, W.,Gao, J.,Huang, Y.,Ouyang, Z. The Crystal Structure of CDK3 and CyclinE1 Complex with Dinaciclib from Biortus To Be Published,
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation