8GW0

Crystal structure of the human dihydroorotase domain in complex with malic acid

Summary for 8GW0

Entry DOI	10.2210/pdb8gw0/pdb
Descriptor	CAD protein, (2S)-2-hydroxybutanedioic acid, ZINC ION, ... (4 entities in total)
Functional Keywords	dihydroorotase, human cad, hydrolase, zn
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	43026.75
Authors	Yang, P.C.,Liu, H.W.,Huang, H.Y.,Huang, C.Y. (deposition date: 2022-09-16, release date: 2023-09-20, Last modification date: 2023-11-15)
Primary citation	Lin, E.S.,Huang, Y.H.,Yang, P.C.,Peng, W.F.,Huang, C.Y. Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil. Biomolecules, 13:-, 2023 Cited by PubMed: 36671534 DOI: 10.3390/biom13010149 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.64 Å)

Structure validation