8GW0
Crystal structure of the human dihydroorotase domain in complex with malic acid
Summary for 8GW0
Entry DOI | 10.2210/pdb8gw0/pdb |
Descriptor | CAD protein, (2S)-2-hydroxybutanedioic acid, ZINC ION, ... (4 entities in total) |
Functional Keywords | dihydroorotase, human cad, hydrolase, zn |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 43026.75 |
Authors | Yang, P.C.,Liu, H.W.,Huang, H.Y.,Huang, C.Y. (deposition date: 2022-09-16, release date: 2023-09-20, Last modification date: 2023-11-15) |
Primary citation | Lin, E.S.,Huang, Y.H.,Yang, P.C.,Peng, W.F.,Huang, C.Y. Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil. Biomolecules, 13:-, 2023 Cited by PubMed: 36671534DOI: 10.3390/biom13010149 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
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