8GUE
Crystal Structure of narbomycin-bound cytochrome P450 PikC with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 238
Summary for 8GUE
Entry DOI | 10.2210/pdb8gue/pdb |
Descriptor | Cytochrome P450 monooxygenase PikC, PROTOPORPHYRIN IX CONTAINING FE, NARBOMYCIN, ... (8 entities in total) |
Functional Keywords | oxidoreductase, narbomycin-bound, pikc, unnatural amino acid |
Biological source | Streptomyces venezuelae |
Total number of polymer chains | 2 |
Total formula weight | 98206.74 |
Authors | |
Primary citation | Pan, Y.,Li, G.,Liu, R.,Guo, J.,Liu, Y.,Liu, M.,Zhang, X.,Chi, L.,Xu, K.,Wu, R.,Zhang, Y.,Li, Y.,Gao, X.,Li, S. Unnatural activities and mechanistic insights of cytochrome P450 PikC gained from site-specific mutagenesis by non-canonical amino acids. Nat Commun, 14:1669-1669, 2023 Cited by PubMed: 36966128DOI: 10.1038/s41467-023-37288-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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