8GUE

Crystal Structure of narbomycin-bound cytochrome P450 PikC with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 238

8GUE の概要

• エントリーDOI: 10.2210/pdb8gue/pdb
• 分子名称: Cytochrome P450 monooxygenase PikC, PROTOPORPHYRIN IX CONTAINING FE, NARBOMYCIN, ... (8 entities in total)
• 機能のキーワード: oxidoreductase, narbomycin-bound, pikc, unnatural amino acid
• 由来する生物種: Streptomyces venezuelae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 98206.74

構造登録者

Li, G.B.,Pan, Y.J.,Li, S.Y.,Gao, X. (登録日: 2022-09-11, 公開日: 2023-02-15, 最終更新日: 2023-11-29)

• 主引用文献: Pan, Y.,Li, G.,Liu, R.,Guo, J.,Liu, Y.,Liu, M.,Zhang, X.,Chi, L.,Xu, K.,Wu, R.,Zhang, Y.,Li, Y.,Gao, X.,Li, S.; Unnatural activities and mechanistic insights of cytochrome P450 PikC gained from site-specific mutagenesis by non-canonical amino acids.; Nat Commun, 14:1669-1669, 2023; PubMed: 36966128; DOI: 10.1038/s41467-023-37288-0

実験手法

X-RAY DIFFRACTION (1.9 Å)