8GTW

SARS-CoV-2 3CL protease (3CLpro) in complex with compound JZD-26

Summary for 8GTW

• Entry DOI: 10.2210/pdb8gtw/pdb
• Descriptor: 3C-like proteinase, (2S)-4-(3,4-dichlorophenyl)-1-[(2-oxidanylidene-1H-quinolin-4-yl)carbonyl]-N-[3,3,3-tris(fluoranyl)propyl]piperazine-2-carboxamide (3 entities in total)
• Functional Keywords: mpro, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 68733.79

Authors

Su, H.X.,Nie, T.Q.,Xie, H.,Li, M.J.,Xu, Y.C. (deposition date: 2022-09-08, release date: 2023-09-13)

• Primary citation: Xu, Y.C.,Zang, Y.,Zhou, Y.; Development of novel inhibitors against SARS-CoV-2 3CLpro; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)