8GTW
SARS-CoV-2 3CL protease (3CLpro) in complex with compound JZD-26
Summary for 8GTW
Entry DOI | 10.2210/pdb8gtw/pdb |
Descriptor | 3C-like proteinase, (2S)-4-(3,4-dichlorophenyl)-1-[(2-oxidanylidene-1H-quinolin-4-yl)carbonyl]-N-[3,3,3-tris(fluoranyl)propyl]piperazine-2-carboxamide (3 entities in total) |
Functional Keywords | mpro, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 2 |
Total formula weight | 68733.79 |
Authors | |
Primary citation | Xu, Y.C.,Zang, Y.,Zhou, Y. Development of novel inhibitors against SARS-CoV-2 3CLpro To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report