8GLE

Crystal Structure of Human CD1b in Complex with Lysosulfatide

8GLE の概要

• エントリーDOI: 10.2210/pdb8gle/pdb
• 分子名称: T-cell surface glycoprotein CD1b, Beta-2-microglobulin, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: immune system, lipid, cd1b, lysosulfatide, lyso
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48923.14

構造登録者

Shahine, A. (登録日: 2023-03-22, 公開日: 2023-09-20, 最終更新日: 2024-05-01)

• 主引用文献: Huang, S.,Shahine, A.,Cheng, T.Y.,Chen, Y.L.,Ng, S.W.,Balaji, G.R.,Farquhar, R.,Gras, S.,Hardman, C.S.,Altman, J.D.,Tahiri, N.,Minnaard, A.J.,Ogg, G.S.,Mayfield, J.A.,Rossjohn, J.,Moody, D.B.; CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.; Cell, 186:4583-4596.e13, 2023; PubMed: 37725977; DOI: 10.1016/j.cell.2023.08.022

実験手法

X-RAY DIFFRACTION (1.85 Å)