8GJC

X-ray crystallographic structure of a beta-hairpin peptide derived from Abeta 17-35. (ORN)LVFFAED(ORN)GAI(N-Me-Ile)GLM

Summary for 8GJC

Entry DOI	10.2210/pdb8gjc/pdb
Descriptor	beta-hairpin peptide derived from Abeta 17-35, METHIONINE, trifluoroacetic acid, ... (5 entities in total)
Functional Keywords	oligomer, tetramer, amyloid, alzheimer's disease, de novo protein
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	3960.42
Authors	Kreutzer, A.G.,Ruttenberg, S.M.,Nowick, J.S. (deposition date: 2023-03-15, release date: 2024-01-17, Last modification date: 2024-01-31)
Primary citation	Ruttenberg, S.M.,Kreutzer, A.G.,Truex, N.L.,Nowick, J.S. beta-Hairpin Alignment Alters Oligomer Formation in A beta-Derived Peptides. Biochemistry, 63:212-218, 2024 Cited by PubMed: 38163326 DOI: 10.1021/acs.biochem.3c00526 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.431 Å)

Structure validation