8GJC

X-ray crystallographic structure of a beta-hairpin peptide derived from Abeta 17-35. (ORN)LVFFAED(ORN)GAI(N-Me-Ile)GLM

8GJC の概要

• エントリーDOI: 10.2210/pdb8gjc/pdb
• 分子名称: beta-hairpin peptide derived from Abeta 17-35, METHIONINE, trifluoroacetic acid, ... (5 entities in total)
• 機能のキーワード: oligomer, tetramer, amyloid, alzheimer's disease, de novo protein
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 3960.42

構造登録者

Kreutzer, A.G.,Ruttenberg, S.M.,Nowick, J.S. (登録日: 2023-03-15, 公開日: 2024-01-17, 最終更新日: 2024-01-31)

• 主引用文献: Ruttenberg, S.M.,Kreutzer, A.G.,Truex, N.L.,Nowick, J.S.; beta-Hairpin Alignment Alters Oligomer Formation in A beta-Derived Peptides.; Biochemistry, 63:212-218, 2024; PubMed: 38163326; DOI: 10.1021/acs.biochem.3c00526

実験手法

X-RAY DIFFRACTION (1.431 Å)