8GCZ
Crystal Structure of HIV-1 LM/HT Clade A/E CRF01 GP120 Core in Complex with ZXC-I-090
Summary for 8GCZ
Entry DOI | 10.2210/pdb8gcz/pdb |
Descriptor | HIV-1 LM/HT Clade A/E CRF01 gp120 core, 2-acetamido-2-deoxy-beta-D-glucopyranose, (3S,5S)-5-(aminomethyl)-N-(4-chloro-3-fluorophenyl)-1-(4-methylpiperazine-1-carbonyl)piperidine-3-carboxamide, ... (5 entities in total) |
Functional Keywords | hiv-1 gp120, clade a/e cf01, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 1 |
Total formula weight | 42771.45 |
Authors | |
Primary citation | Ding, S.,Tolbert, W.D.,Zhu, H.,Lee, D.,Marchitto, L.,Higgins, T.,Zhao, X.,Nguyen, D.,Sherburn, R.,Richard, J.,Gendron-Lepage, G.,Medjahed, H.,Mohammadi, M.,Abrams, C.,Pazgier, M.,Smith III, A.B.,Finzi, A. Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC. Viruses, 15:-, 2023 Cited by PubMed: 37243271DOI: 10.3390/v15051185 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report