8GB2
Crystal structure of Apo-SAMHD1
Summary for 8GB2
| Entry DOI | 10.2210/pdb8gb2/pdb |
| Descriptor | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION (3 entities in total) |
| Functional Keywords | samhd1, dntpase, hydrolase, dimer, dimeric |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 239440.91 |
| Authors | Egleston, M.,Dong, L.,Howlader, A.H.,Bhat, S.,Orris, B.,Bianchet, M.A.,Greenberg, M.M.,Stivers, J.T. (deposition date: 2023-02-24, release date: 2023-06-07, Last modification date: 2023-11-01) |
| Primary citation | Egleston, M.,Dong, L.,Howlader, A.H.,Bhat, S.,Orris, B.,Bianchet, M.A.,Greenberg, M.M.,Stivers, J.T. Deoxyguanosine-Linked Bifunctional Inhibitor of SAMHD1 dNTPase Activity and Nucleic Acid Binding. Acs Chem.Biol., 18:2200-2210, 2023 Cited by PubMed: 37233733DOI: 10.1021/acschembio.3c00118 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.07 Å) |
Structure validation
Download full validation report
