8G9A

Crystal structure of a resurrected ancestor (AncRNase) of the pancreatic-type RNases 2 and 3 sub-families

8G9A の概要

• エントリーDOI: 10.2210/pdb8g9a/pdb
• 分子名称: a resurrected ancestor (AncRNase) of the pancreatic-type RNases 2 and 3 sub-families, SULFATE ION, ACETATE ION, ... (5 entities in total)
• 機能のキーワード: ancestral sequence reconstruction, asr, eosinophil-derived neurotoxin, edn, rnase 2, eosinophil cationic protein, ecp, rnase 3, ribonuclease, hydrolase, transphosphorylase
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 64746.69

構造登録者

Tran, T.T.Q.,Pham, N.T.H.,Calmettes, C.,Doucet, N. (登録日: 2023-02-21, 公開日: 2024-02-28, 最終更新日: 2024-05-29)

• 主引用文献: Tran, T.T.Q.,Narayanan, C.,Loes, A.N.,Click, T.H.,Pham, N.T.H.,Letourneau, M.,Harms, M.J.,Calmettes, C.,Agarwal, P.K.,Doucet, N.; Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases.; J.Biol.Chem., 300:107280-107280, 2024; PubMed: 38588810; DOI: 10.1016/j.jbc.2024.107280

実験手法

X-RAY DIFFRACTION (2.03 Å)