8G89

HSD17B13 in complex with cofactor and inhibitor

8G89 の概要

• エントリーDOI: 10.2210/pdb8g89/pdb
• 関連するPDBエントリー: 8G84
• 分子名称: Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3-fluoro-N-({(1r,4r)-4-[(2-fluorophenoxy)methyl]-1-hydroxycyclohexyl}methyl)-4-hydroxybenzamide, ... (4 entities in total)
• 機能のキーワード: 17 beta-hydroxysteroid dehydrogenase 13; lipid droplet associated protein; inhibitor, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Canis lupus familiaris (dog)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72446.68

構造登録者

Liu, S. (登録日: 2023-02-17, 公開日: 2023-08-09, 最終更新日: 2023-09-06)

• 主引用文献: Liu, S.,Sommese, R.F.,Nedoma, N.L.,Stevens, L.M.,Dutra, J.K.,Zhang, L.,Edmonds, D.J.,Wang, Y.,Garnsey, M.,Clasquin, M.F.; Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13.; Nat Commun, 14:5158-5158, 2023; PubMed: 37620305; DOI: 10.1038/s41467-023-40766-0

実験手法

X-RAY DIFFRACTION (2.222 Å)