8G73
SARS-CoV-2 spike/Nb3 complex with 2 RBDs up and 3 Nb3 bound at 2.5 A
Summary for 8G73
Entry DOI | 10.2210/pdb8g73/pdb |
EMDB information | 29792 29793 29794 29795 29796 29797 29798 29799 29802 29803 29804 29805 29806 |
Descriptor | Nanosota-3, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | sars-cov-2, viral protein-immune system complex, nanobody, viral protein/immune system |
Biological source | Vicugna pacos (alpaca) More |
Total number of polymer chains | 6 |
Total formula weight | 465962.16 |
Authors | |
Primary citation | Ye, G.,Pan, R.,Bu, F.,Zheng, J.,Mendoza, A.,Wen, W.,Du, L.,Spiller, B.,Wadzinski, B.E.,Liu, B.,Perlman, S.,Li, F. Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19. J.Virol., 97:e0144823-e0144823, 2023 Cited by PubMed: 37855638DOI: 10.1128/jvi.01448-23 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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