8G73

SARS-CoV-2 spike/Nb3 complex with 2 RBDs up and 3 Nb3 bound at 2.5 A

8G73 の概要

• エントリーDOI: 10.2210/pdb8g73/pdb
• EMDBエントリー: 29792 29793 29794 29795 29796 29797 29798 29799 29802 29803 29804 29805 29806
• 分子名称: Nanosota-3, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, viral protein-immune system complex, nanobody, viral protein/immune system
• 由来する生物種: Vicugna pacos (alpaca); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 465962.16

構造登録者

Ye, G.,Bu, F.,Liu, B.,Li, F. (登録日: 2023-02-16, 公開日: 2024-01-24)

• 主引用文献: Ye, G.,Pan, R.,Bu, F.,Zheng, J.,Mendoza, A.,Wen, W.,Du, L.,Spiller, B.,Wadzinski, B.E.,Liu, B.,Perlman, S.,Li, F.; Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19.; J.Virol., 97:e0144823-e0144823, 2023; PubMed: 37855638; DOI: 10.1128/jvi.01448-23

実験手法