8G5M
Cryo-EM structure of the Mismatch Locking Complex (III) of Human Mitochondrial DNA Polymerase Gamma
Summary for 8G5M
Entry DOI | 10.2210/pdb8g5m/pdb |
EMDB information | 29749 |
Descriptor | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, Mismatched RNA Primer, ... (4 entities in total) |
Functional Keywords | mitochondrial dna polymerase, dna proofreading, mismatch locking, replication-dna-rna complex, replication/dna/rna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 266645.31 |
Authors | Nayak, A.R.,Buchel, G.,Herbine, K.H.,Sarfallah, A.,Sokolova, V.O.,Zamudio-Ochoa, A.,Temiakov, D. (deposition date: 2023-02-13, release date: 2024-01-10) |
Primary citation | Buchel, G.,Nayak, A.R.,Herbine, K.,Sarfallah, A.,Sokolova, V.O.,Zamudio-Ochoa, A.,Temiakov, D. Structural basis for DNA proofreading. Nat Commun, 14:8501-8501, 2023 Cited by PubMed: 38151585DOI: 10.1038/s41467-023-44198-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.58 Å) |
Structure validation
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