8G3I

Non-ribosomal PCP-C didomain (thioether stabilised glycolic acid) acceptor bound state

Summary for 8G3I

• Entry DOI: 10.2210/pdb8g3i/pdb
• Descriptor: PCP-C didomain, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(2-hydroxyethyl)sulfanyl]ethyl}-beta-alaninamide (3 entities in total)
• Functional Keywords: nrps, c-domain, pcp-domain, biosynthetic protein
• Biological source: Thermobifida fusca YX
• Total number of polymer chains: 2
• Total formula weight: 115780.70

Authors

Ho, Y.T.C.,Izore, T.,Cryle, M.J. (deposition date: 2023-02-08, release date: 2023-06-14, Last modification date: 2023-12-27)

• Primary citation: Ho, Y.T.C.,Izore, T.,Kaczmarski, J.A.,Marschall, E.,Ratnayake, M.,Tailhades, J.,Steer, D.L.,Schittenhelm, R.B.,Tosin, M.,Jackson, C.J.,Cryle, M.J.; Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin; Front Catal, 3:-, 2023; DOI: 10.3389/fctls.2023.1184959

Experimental method

X-RAY DIFFRACTION (3.02 Å)