8G35

Crystal structure of F182L-CYP199A4 in complex with (S)-4-(2-hydroxy-3-oxobutan-2-yl)benzoic acid

8G35 の概要

• エントリーDOI: 10.2210/pdb8g35/pdb
• 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, 4-[(2S)-2-hydroxy-3-oxobutan-2-yl]benzoic acid, ... (5 entities in total)
• 機能のキーワード: cytochrome, bacterial p450, oxidoreductase
• 由来する生物種: Rhodopseudomonas palustris HaA2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45413.57

構造登録者

Lee, J.H.Z.,Bell, S.G.,Bruning, J.B. (登録日: 2023-02-06, 公開日: 2023-05-17, 最終更新日: 2024-05-22)

• 主引用文献: Miller, J.C.,Lee, J.H.Z.,Mclean, M.A.,Chao, R.R.,Stone, I.S.J.,Pukala, T.L.,Bruning, J.B.,De Voss, J.J.,Schuler, M.A.,Sligar, S.G.,Bell, S.G.; Engineering C-C Bond Cleavage Activity into a P450 Monooxygenase Enzyme.; J.Am.Chem.Soc., 145:9207-9222, 2023; PubMed: 37042073; DOI: 10.1021/jacs.3c01456

実験手法

X-RAY DIFFRACTION (2 Å)